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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED15
All Species:
37.27
Human Site:
T574
Identified Species:
74.55
UniProt:
Q96RN5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RN5
NP_001003891.1
788
86753
T574
K
S
L
L
D
I
L
T
D
P
S
K
R
C
P
Chimpanzee
Pan troglodytes
XP_525528
947
103470
T733
K
S
L
L
D
I
L
T
D
P
S
K
R
C
P
Rhesus Macaque
Macaca mulatta
XP_001084461
858
93524
T644
K
S
L
L
D
I
L
T
D
P
S
K
R
C
P
Dog
Lupus familis
XP_849892
749
82534
T535
K
S
L
L
D
I
L
T
D
P
S
K
R
C
P
Cat
Felis silvestris
Mouse
Mus musculus
Q924H2
792
87042
T575
K
S
L
L
D
I
L
T
D
P
S
K
R
C
P
Rat
Rattus norvegicus
NP_001101795
790
86778
T576
K
S
L
L
D
I
L
T
D
P
S
K
R
C
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519670
319
35067
L115
Y
L
E
K
L
K
Q
L
S
K
Y
I
E
P
L
Chicken
Gallus gallus
XP_415235
821
90508
T607
K
S
L
L
D
I
L
T
D
P
S
K
R
C
P
Frog
Xenopus laevis
Q6NS15
777
86667
T563
K
S
L
L
D
I
L
T
D
P
N
K
R
C
P
Zebra Danio
Brachydanio rerio
Q7ZVN7
809
89844
T596
K
S
L
L
N
I
L
T
D
P
N
T
R
C
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y149
749
80507
S521
V
E
K
M
T
K
M
S
K
L
L
E
I
L
C
Honey Bee
Apis mellifera
XP_623876
486
52949
E282
L
K
C
E
V
V
L
E
K
V
D
F
K
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.8
91
89.2
N.A.
90.5
91.7
N.A.
37.5
73.3
66.7
61.5
N.A.
31.6
28.6
N.A.
N.A.
Protein Similarity:
100
82.8
91.3
90.6
N.A.
93
93.8
N.A.
39.5
79.6
74.8
69.8
N.A.
45.6
39.4
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
93.3
80
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
100
93.3
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
75
9
% C
% Asp:
0
0
0
0
67
0
0
0
75
0
9
0
0
0
0
% D
% Glu:
0
9
9
9
0
0
0
9
0
0
0
9
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
75
0
0
0
0
0
9
9
0
0
% I
% Lys:
75
9
9
9
0
17
0
0
17
9
0
67
9
0
0
% K
% Leu:
9
9
75
75
9
0
84
9
0
9
9
0
0
9
9
% L
% Met:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
17
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
75
0
0
0
9
75
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
75
9
0
% R
% Ser:
0
75
0
0
0
0
0
9
9
0
59
0
0
0
9
% S
% Thr:
0
0
0
0
9
0
0
75
0
0
0
9
0
0
0
% T
% Val:
9
0
0
0
9
9
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _